ABOUT AACR 2020

Welcome to the AACR website-

 AACR 2020 is going to be beginning on 24 Apr and ending on 29 Apr 2020. AACR 2020 is truly an amazing Meeting which will cover the topics of Medical, Health Care, Oncology, Cancer, Cancer Treatment and Cancer Diagnosis and much more. It will be a marvelous Medical and Cancer Treatment and Cancer Diagnosis Meeting at San Diego Convention Center, San Diego, California USA.

 The AACR was founded in 1907 by a group of 11 physicians and scientists interested in research, "to further the investigation and spread the knowledge of cancer." Today, the AACR accelerates progress toward the prevention and cure of cancer by promoting research, education, communication, and collaboration. Annual Meeting of the American Association for Cancer Research is organized annually. The annual meeting continues to grow! It will be expected to reach 19000 attendees this year.

Get ready for San Diego!

This expansive scientific programme will be held in the impressive San Diego Convention Center, located in 111 W Harbor Dr, San Diego, CA 92101, California, USA. This congress centre has also played host to the annual meeting on multiple occasions, and repeat visitors will be familiar with its bright, open spaces, generous meeting rooms and superb location. Hotel accommodations are now available at our website. For individual hotel booking best resource is our website. Hotels in close proximity to the venue are available to book directly at special rates. You just have to fill out the housing form, check for available options, and choose the hotel available and the one you like from the list, book directly by online secure payments. This will give delegates access to the best locations at favorable rates, and we strongly recommended booking your hotel through our website.

We look forward to welcoming you to San Diego!

Venue: San Diego Convention Center, San Diego, California USA

Address: 111 W Harbor Dr, San Diego, CA 92101, USA

  • 19000 Attendees

  • 1230 Exhibitors

  • 130 Countries

Program Overview Schedule

24-Apr- 29-Apr-2020 @ 8:00 PM-6:30 PM

8:00 PM-6:30 PM

24-Apr- 29-Apr-2020

    On Friday, April 24, 2020, a program of Educational Sessions and Methods Workshops will be presented beginning at 3 p.m. The Opening Ceremony and the Opening Plenary Session will take place on Sunday morning, April 26. The meeting will conclude at 1:30 p.m. on Wednesday, April 29. The 2020 Program in Progress follows. 

    • Educational Sessions
    • Methods Workshops
    • Plenary Sessions
    • Major Symposia
    • Meet-the-Expert Sessions
    • Advances in Diagnostics and Therapeutics
    • Advances in Organ Site Research
    • Advances in Prevention and Interception
    • Advances in the Science of Cancer Health Disparities
    • Forums

Educational Sessions Schedule

24-Apr- 29-Apr-2020 @ 8:00 AM-6:30 PM

8:00 AM-6:30 PM

24-Apr- 29-Apr-2020

    Approaches for Utilizing the Microbiome in Cancer Epidemiology Research

    Biomarker Studies: Study Design and Statistical Considerations

    CAR-T Therapy State of the Art

    Characterizing Cancer Disparities Nationally and Internationally Using Publicly Available Data

    Chemistry to the Clinic: Part 1: Lead Optimization in Cancer Drug Discovery

    Chemistry to the Clinic: Part 2: Novel Chemical Tools and Leads for Unprecedented Targets

    Chemistry to Clinic: Part 3: Unconventional Modalities to Extend the Antitumor Target Space

    Co-Evolution of Tumor and Microenvironment in Cancer Metastasis

    Convergence

    Developing Standardized Platforms for Immune Monitoring in Cancer Immunotherapy Clinical Trials

    Diverse Functions of Neutrophils in Cancer

    Drug Development in China/Asia

    The Endothelium and Fluid Flows: Linking Metastasis and Immunity

    The Evolution of the Art and Science of Go/No Go Decisions in Cancer Drug Development

    Extracellular Vesicles and Intercellular Communication in Cancer

    FDA Session on Introduction to Oncology Drug Regulation

    FDA Session on Topics in Oncology Regulation

    Fibroblasts in the Driver's Seat: Impact on Tumor Progression and Therapy Resistance

    Fluorescence Image-Guided Surgery for Improved Clinical Outcomes

    From Cancer Genomics to the 3D Organization of the Genome

    Genetic Predispositions to Childhood Lekemias: Implications for Pathogenesis and Screening

    Host Versus Tumor Autophagy in Cancer

    Immune-Targeted Biomarker Incorporation into Therapeutic Decision Making

    Integrating Tumor Immunology and Molecular Epidemiology

    Intersection of Radiation and Immune Therapy

    Liquid Biopsies for Early Detection of Cancer

    Metabolic Drivers of Cancer

    Modulation of the Gut Microbiome to Treat Dysbiosis and Cancer

    Molecular Regulation of Cancer Inflammation, Progression and Treatment Resistance

    Obesity: Local and Systemic Inflammation Affecting Cancer

    Oncolytic Virus Therapy

    Ordering Genomic Changes as Actionable Targets in Pediatric Cancers

    Organoids as Model Systems in Cancer

    Pancreatic Tumor Microenvironment

    Pathology 101

    Personalized Circulating Tumor DNA Analysis for Minimal Residual Disease Detection

    Precision Medicine in 2020

    Preleukemia and Clonal Hematopoiesis

    Quantitative Approaches to Study Cancer Evolution and Heterogeneity

    Resistance to Therapies and Cancer Cell Dormancy

    Single Cell and Spatial Genomics

    Stromal Niches for Organ-Tropic Metastasis

    Systems Biology Approaches to Cancer

    Targeting Cancer Neoantigens

    Tools for Machine Learning in Cancer Image Analysis

    Tumor Immunology and Immunotherapy for Nonimmunologists: Roundtable Discussions

    Tumor Immunology and Immunotherapy for Nonimmunologists: Standard Cancer Therapies are Ultimately Immunotherapies

    Update on Young Women’s Breast Cancer

    Vascular-Immune Cell Cross Talk: Implications for Cancer Immunotherapy

Methods Workshops Schedule

24-Apr- 29-Apr-2020 @ 8:00 AM-6:30 PM

8:00 AM-6:30 PM

24-Apr- 29-Apr-2020

    Circulating Cell Free DNA to Guide Prostate Cancer Treatment with PARP

    Clinical Trial Design: Part 1: The ABCs of Doing Cancer Clinical Trials

    Clinical Trial Design: Part 2: Novel Trial Designs

    Clinical Trial Design: Part 3: Biomarker-Directed Clinical Trials

    Clinical Trial Design: Part 4

    Controversies in Replication cfDNA Measurements

    Deciphering and Targeting Lysosomes in Cancer

    Defining the Significance of BRCA1 Variants of Unknown Significance

    Defining Tumor Organ-systems with Single Cell Transcriptomics

    Designing Biomarker Studies to Achieve Desired Clinical Applications

    Game-Changing Technologies for High Through-Put Functional Characterization of Cancer Gene Variants

    Metabolomic Methods for Cancer Research

    Methods for Utilizing the Microbiome in Cancer Epidemiology Research

    Modeling Tumor Dormancy

    Novel Imaging Strategies in the Metastatic Niche

    Peering through the Looking Glass: Imaging and the Metastatic Niche

    Sample Size and Power Workshop for Basic, Translational, and Clinical Studies

Major Symposia Schedule

24-Apr- 29-Apr-2020 @ 8:00 AM-6:30 PM

8:00 AM-6:30 PM

24-Apr- 29-Apr-2020

    AACR-Bayard D. Clarkson Symposium: Single-Cell Anaysis of Tumor Heterogeneity

    Advancing Epigenetic Therapies for Solid Tumors

    Artificial Intelligence and Machine Learning for Regulatory Use

    At the Roots of Cancer: Biology and Regulation of the Hippo-YAP Pathway

    Blood Biopsy for Response Monitoring

    Bone Marrow Sensing of Distant Tumors: From Early Detection to Possible Therapy 

    Cell-Based Therapies (Imm7)

    The Changing Etiology of Liver Cancer: Needs for Prevention

    Characterizing and Managing Cancer as a Complex Adaptive System 

    Circadian Rhythms and Cancer

    Clinical Trials and Clinical Utility 

    Convergence of Artificial Intelligence, Big Data, and Prediction in Cancer 

    Deregulation of Histone Modifiers in Cancer

    Diverse Populations and Cancer

    Earlier Detection of Cancer: Who to Screen, Where to Screen, and What to Screen?

    Effects of Systemic Tumor-host Responses in Progression and Therapy Responses

    Escaping Immune Surveillance

    Evolution and Development of Resistance to Therapy 

    FDA Special Session with Richard Pazdur

    Genomic Instability

    Germline-Somatic Interactions in Cancer Risk and Tumor Evolution 

    Hematologic Malignancies

    Immune Exhaustion in Cancer Therapies

    Impact of a Brexit on Oncology Drug Development and Regulation

    Interactions between the Local Microenvironment and the Cancer Cells in Progression and Therapy Responses

    Liquid Biopsies: From Validation to Clinical Utility

    Mammalian Sirtuins, Energy Bioenergetics, Metabolism, and Carcinogenesis

    The Matrix Reloaded: Influences of the Extracellular Matrix on Tumor Progression

    Metabolism: The New Kids on the Block in Cancer Care

    Metastasis: Evidence and Clinical Implications of Early Dissemination 

    The Microbiome as an Orchestrator of Immunity and Cancer Immunotherapy

    Minimal Residual Disease: From Bench to Bedside 

    Minorities in Cancer Research Scientific Symposium

    Molecular Determinants and Dynamics of Metastasis

    Multilevel Consideration of Cancer Health Disparities: Contextual Factors to Molecular Features 

    The Next Generation of Precision Cancer Medicine:  Recognizing and Exploiting the Complexity

    Obesity and Cancer: When Systemic Metabolism Cell Metabolism

    Organ-Specific Immunity

    Pediatric Oncology: Discovery, Development, Distribution

    Prediagnostic Esposures and Tumor Mutational Signatures in Population Studies

    Predictive Biomarkers

    Presidential Select Symposium: Engaging Cancer Patients as Partners in the Research Process

    Recently Approved Breakthrough Therapies and New Approval Endpoints

    Regulation and Function of TP53 

    Regulatory Considerations for Liquid Biopsy

    The Science of Survivorship: Long-term Survivorship in Vulnerable Populations

    Systematic Elucidation of Nononogene Targets

    Systems Biology and Cancer Immunology

    Systems Epigenetics in Hormone-Driven Cancers 

    Tobacco Session

    Transcriptional and Gene-Regulatory States: How They Relate to Lineage Origin and Plasticity in Pediatric Cancer

    Tumor Metabolism and DNA Damage Response

    Vascular Regulation of Anti-tumor Immunity

Diagnostics & Therapeutics Schedule

24-Apr- 29-Apr-2020 @ 8:00 AM-6:30 PM

8:00 AM-6:30 PM

24-Apr- 29-Apr-2020

    Cooperativity of Tumor Clones

    Innate Immunity and Complement in Solid Tumors

    Intratumoral Approaches to Immunotherapy 

    Liquid Biopsy in Brain Tumors and Metastases 

    Modeling Treatment Response in Patient-Derived Organoids 

    Molecular Imaging 

    Nonpharmacologic Approaches to Improving Survival and Patient-Reported Outcomes 

    Proton Therapy 

    Recent Progress in Boron Neutron Capture Therapy

    Regulation of the Immune Microenvironment by Glycosylation

    The Remarkable Utility of Proximate Biologic Samples: Molecular Detection of Endometrial Cancer

    RNA Editing in Cancer Pathophysiology

    Small Molecule Protein Degraders

    T-Cell Bispecifics: What Have We Learned About T-Cell Engagers in the Clinic?

    Tumor Treating Fields- A Fourth Modality in Cancer Treatment

    Vaccines

Organ Site Research Schedule

24-Apr- 29-Apr-2020 @ 8:00 AM-6:30 PM

8:00 AM-6:30 PM

24-Apr- 29-Apr-2020

    Advances in Brain Metastases 

    Advances in Gastric Cancer

    Advances in Multiple Myeloma

    Advances in Pancreatic Cancer 

    Biologic Therapy Advances in Pediatric Tumors

    The Changing Face of Ovarian Cancer 

    Esophageal Cancer Equal Biology to Translational Medicine

    Genetic Predisposition in Hematologic Malignancies

    Genitourinary, Bladder, and Renal Cancers

    Neuroendocrine Tumors: Genomics, Genetics, and Therapy

    Small Cell Lung Cancer: A Glimmer of Light at the End of the Tunnel

Prevention, Interception & Cancer Health Disparities Schedule

24-Apr- 29-Apr-2020 @ 8:00 AM-6:30 PM

8:00 AM-6:30 PM

24-Apr- 29-Apr-2020

    Advances in Prevention and Interception

    Engineering Meets Biology

    Role of Chronic Stress in the Etiology of Cancer 

    Spectrum of Premalignant and Malignant Genomic Alterations in the “Healthy” Population 

    Advances in the Science of Cancer Health Disparities

    Novel Applications of Clinical Trials Research to Studying Disparities

    The Science of Cancer Health Disparities

Forums Schedule

24-Apr- 29-Apr-2020 @ 8:00 AM-6:30 PM

8:00 AM-6:30 PM

24-Apr- 29-Apr-2020

    B Cells in Solid Tumors: Good or Bad

    Biden Cancer Initiative

    Cancer Imaging: Separating the Hype from the Hope in Radiomics and Machine Learning

    Challenges and Opportunities of International Consortia

    The Changing Economics of Cancer

    Drugging the Undruggable

    Elimination of HPV and Related Cancers

    Fighting the IL-1 Inflammatory Pathway

    The Future of the In Vitro Clinical Test Regulation

    Immuno-oncology Combination Trials: What Went Wrong?

    Implementation Science for Evidence-Based Cancer Prevention and Early Detection Practices in Defined Diverse Populations

    The Integration of Nanotechnologies and Bioengineering for Cancer Research

    Minorities in Cancer Research Forum

    The Science of Global Community Outreach

    Science of Survivorship: The Intersection of Survivorship and Aging

    Updates on Atlas Development
     

Meet-the-Experts Schedule

24-Apr- 29-Apr-2020 @ 8:00 AM-6:30 PM

8:00 AM-6:30 PM

24-Apr- 29-Apr-2020

    A-I DNA Editing in Mutation and Diversity

    The ALK Oncogene and Neuroblastoma - Yael P. Mosse, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

    Amyloidosis - Suzanne Lentzsch, Columbia University, New York, New York

    Approaches to Combination Therapy - Peter K. Sorger, Harvard Medical School, Boston, Massachusetts

    ATAC Sequencing

    Basic Immunology - Adrian Hayday, Francis Crick Institute, London, United Kingdom

    Basic Immunology and Cancer Immunobiology

    Big Data

    Biology of Circulating Tumor Cells in Cancer Metastasis

    Biomedical Informatics and Artificial Intellengence

    Brain Tumor Biology: Malignant Networks in the Brain, and How to Target Them - Frank A. Winkler, German Cancer Research Center, Heidelberg, Germany

    Breast Cancer Stem Cells: Translating Biology to the Clinic - Max S. Wicha, University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan

    Chemical Methods to Decipher the Role of Individual Kinases and Their Cellular Signaling Networks

    Circulating Cell-Free DNA to Guide Prostate Cancer Treatment with PARP Inhibition - Johann S. DeBono, Institute of Cancer Research, Sutton, United Kingdom

    CODEX Multiplex Imaging

    Combination Therapies: Immunotherapy and Radiation

    Detection, Biology, and Clinical Relevance of CTC Clusters

    Developmental Models of Pediatric Brain Tumors - Peter B. Dirks, The Hospital for Sick Children, Toronto, Ontario

    Diet, the Gut Microbiome, and Colorectal Cancer - Andrew T. chan, Massachusetts General Hospital, Boston,Mas.

    Disparities in Breast Cancer Prevention Research

    DNA Repair

    Drugging the Undruggable: The Myc Oncogene, as a Case Study

    Engaging and Involving Patients in Translational Cancer Research - Bodour Salhia, University of Southern California

    High Dimensional Analysis using Mass Cytometry - Kara L. Davis, Stanford University, Stanford, California

    Immune Checkpoint Pathways, Melanoma, Surgery

    Lung Cancer: Trials - Alice T. Shaw, Massachusetts General Hospital Cancer Center, Boston, Massachusetts

    Metabolism: PI3K - Lewis C. Cantley, Weill Cornell Medical College, New York- Presbyterian Hospital, New York

    Modeling of Pediatric Brain Tumors

    Natural Killer Cells

    New Single Cell Methods for Oncology and Immuno-oncology - James R. Heath, California Institute of Technology, Pasadena, California

    Novel Radiopharmaceuticals for Cancer Diagnosis and  Diagnosis and Therapy, and Methods to Predict and Monitor the Response of  Tumors to Chemotherapy

    Novel Therapeutic Strategies in Multiple Myeloma - Kenneth C. Anderson, Dana-Farber Cancer Institute, Boston

    Obesity: Changing the Landscape for Cancer Risk in Populations

    Prostate Cancer Health Disparity - Timothy R. Rebbeck, Harvard School of Public Health, Boston, Massachusetts

    Radiation and Immunotherapy in Breast Cancer

    Single Cell Genomics in Cancer to Deconvolute Tumor Heterogeneity

    Systems Biology: Experimental and Mathematical, Computational Analysis

    Universal Cancer Biomarker - Simple Test Using Gold Nanoparticles that Instantly Change Color to Determine if the 3D Nanostructures of Cancer DNA are Present - Matt Trau, The University of Queensland, Brisbane, Australia

    Uses of CRISPR Technology in Translational Cancer Research - René Bernards, Netherlands Cancer Institute, Amsterdam

    Using Zebrafish to Model Pediatric Cancer and Identify New Pathways for Targeted Drug Therapy - A. Thomas Look, Dana-Farber Cancer Institute, Boston, Massachusetts

    What Cancer Genomes Tell Us About the Origins of Breast Cancer - Olufunmilayo I. Olopade, University of Chicago Medical Center, Chicago, Illinois

Plenary Sessions Schedule

24-Apr- 27-Apr-2020 @ 8:00 AM-6:30 PM

8:00 AM-6:30 PM

24-Apr- 27-Apr-2020

    Friday, April 24, 2020
    Opening Plenary
    Achieving Equitable Patient Care through Precision and Convergent Cancer Science
    Chair: John D. Carpten, University of Southern California Keck School of Medicine, Los Angeles, California

    Physicist vs. physician: Digitizing clinical assessment, and using it for evidence-based prediction of outcomes
    Peter Kuhn, University of Southern California Michelson Center for Convergent Bioscience, Los Angeles, California

    Title to be announced
    Jorge J. Nieva, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California

    Therapeutic implications of DNA repair defects in cancer
    Alan Ashworth, University of California San Francisco Helen Diller Family Comprehensive Cancer Center, San Francisco, California

    Defining the actionable genome
    David B. Solit, Memorial Sloan Kettering Cancer Center, New York, New York

    Title to be announced
    Levi A. Garraway, Eli Lilly and Company, Indianapolis, Indiana 

    Next generation CAR T cells designed to overcome tumor resistance
    Crystal L. Mackall, Stanford University School of Medicine, Stanford, California

    Title to be announced
    E. John Wherry, University of Pennsylvania, Philadelphia, Pennsylvania


    Saturday, April 25, 2020
    Clinical and Translational Research in Diverse Populations
    Chair: Lisa A. Newman, Weill Cornell Medicine, New York, New York

    Title to be announced
    Olusegun I. Alatise, Obafemi Awolowo University, Ile-Ife, Osun, Nigeria

    Spliceomics: Alternative RNA splicing as a source of ancestry-related molecular targets in precision oncology and cancer disparities
    Steven R. Patierno, Duke Cancer Institute, Durham, North Carolina

    The DARC side of breast cancer disparities: Links to African ancestry and immunological tumor responses
    Melissa B. Davis, Weill Cornell Medicine, New York, New York

    Genomic and epigenomic studies of Cholangiocarcinoma in diverse populations
    Bin Tean Teh, National Cancer Center Singapore, Singapore

     

    Sunday, April 26, 2020
    Manipulating the Immune System in Cancer Therapy 
    Chair: Padmanee Sharma, The University of Texas MD Anderson Cancer Center, Houston, Texas
     

    T-cell therapy targeting unique cancer mutations
    Steven A. Rosenberg, National Cancer Institute, Bethesda, Maryland

    Redirecting T-cells for cancer immunotherapy using next generation bispecific antibodies and fusion proteins
    Pablo Umana, Roche Innovation Center Zurich, Zurich, Switzerland 

    Taming the beast: Strategies to target the immune suppressive macrophage to enhance cancer immune therapy
    Judith A. Varner, University of California San Diego Moores Cancer Center, La Jolla, California

    Mismatch repair deficiency: A connection between the immune system and cancer genetics
    Dung T. Le, Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland
     

    Monday, April 27, 2020
    Pathogen-Related Cancers: Implications for Populations and Public Health 
    Chair: Douglas R. Lowy, National Cancer Institute, Bethesda, Maryland

    Screening nasopharyngeal carcinoma using plasma Epstein-Barr virus DNA: technological and clinical insights
    Yuk Ming Dennis Lo, The Chinese University of Hong Kong, Shatin, Hong Kong

    Hepatitis B and C virus-related hepatocellular carcinoma in the era of highly active antiviral therapies
    Jean-Michel Pawlotsky, Institut Mondor de Recherche Biomédicale, INSERM U955, Créteil, France

    HIV and cancer: From despair to gene therapy
    Ariela Noy, Memorial Sloan Kettering Cancer Center, New York, New York

    Title to be announced
    Cornelia L. Trimble, Johns Hopkins University, Baltimore, Maryland

Program Overview Schedule24-Apr- 29-Apr-2020 @ 8:00 PM

On Friday, April 24, 2020, a program of Educational Sessions and Methods Workshops will be presented beginning at 3 p.m. The Opening Ceremony and the Opening Plenary Session will take place on Sunday morning, April 26. The meeting will conclude at 1:30 p.m. on Wednesday, April 29. The 2020 Program in Progress follows. 

  • Educational Sessions
  • Methods Workshops
  • Plenary Sessions
  • Major Symposia
  • Meet-the-Expert Sessions
  • Advances in Diagnostics and Therapeutics
  • Advances in Organ Site Research
  • Advances in Prevention and Interception
  • Advances in the Science of Cancer Health Disparities
  • Forums

Educational Sessions Schedule24-Apr- 29-Apr-2020 @ 8:00 AM

Approaches for Utilizing the Microbiome in Cancer Epidemiology Research

Biomarker Studies: Study Design and Statistical Considerations

CAR-T Therapy State of the Art

Characterizing Cancer Disparities Nationally and Internationally Using Publicly Available Data

Chemistry to the Clinic: Part 1: Lead Optimization in Cancer Drug Discovery

Chemistry to the Clinic: Part 2: Novel Chemical Tools and Leads for Unprecedented Targets

Chemistry to Clinic: Part 3: Unconventional Modalities to Extend the Antitumor Target Space

Co-Evolution of Tumor and Microenvironment in Cancer Metastasis

Convergence

Developing Standardized Platforms for Immune Monitoring in Cancer Immunotherapy Clinical Trials

Diverse Functions of Neutrophils in Cancer

Drug Development in China/Asia

The Endothelium and Fluid Flows: Linking Metastasis and Immunity

The Evolution of the Art and Science of Go/No Go Decisions in Cancer Drug Development

Extracellular Vesicles and Intercellular Communication in Cancer

FDA Session on Introduction to Oncology Drug Regulation

FDA Session on Topics in Oncology Regulation

Fibroblasts in the Driver's Seat: Impact on Tumor Progression and Therapy Resistance

Fluorescence Image-Guided Surgery for Improved Clinical Outcomes

From Cancer Genomics to the 3D Organization of the Genome

Genetic Predispositions to Childhood Lekemias: Implications for Pathogenesis and Screening

Host Versus Tumor Autophagy in Cancer

Immune-Targeted Biomarker Incorporation into Therapeutic Decision Making

Integrating Tumor Immunology and Molecular Epidemiology

Intersection of Radiation and Immune Therapy

Liquid Biopsies for Early Detection of Cancer

Metabolic Drivers of Cancer

Modulation of the Gut Microbiome to Treat Dysbiosis and Cancer

Molecular Regulation of Cancer Inflammation, Progression and Treatment Resistance

Obesity: Local and Systemic Inflammation Affecting Cancer

Oncolytic Virus Therapy

Ordering Genomic Changes as Actionable Targets in Pediatric Cancers

Organoids as Model Systems in Cancer

Pancreatic Tumor Microenvironment

Pathology 101

Personalized Circulating Tumor DNA Analysis for Minimal Residual Disease Detection

Precision Medicine in 2020

Preleukemia and Clonal Hematopoiesis

Quantitative Approaches to Study Cancer Evolution and Heterogeneity

Resistance to Therapies and Cancer Cell Dormancy

Single Cell and Spatial Genomics

Stromal Niches for Organ-Tropic Metastasis

Systems Biology Approaches to Cancer

Targeting Cancer Neoantigens

Tools for Machine Learning in Cancer Image Analysis

Tumor Immunology and Immunotherapy for Nonimmunologists: Roundtable Discussions

Tumor Immunology and Immunotherapy for Nonimmunologists: Standard Cancer Therapies are Ultimately Immunotherapies

Update on Young Women’s Breast Cancer

Vascular-Immune Cell Cross Talk: Implications for Cancer Immunotherapy

Methods Workshops Schedule24-Apr- 29-Apr-2020 @ 8:00 AM

Circulating Cell Free DNA to Guide Prostate Cancer Treatment with PARP

Clinical Trial Design: Part 1: The ABCs of Doing Cancer Clinical Trials

Clinical Trial Design: Part 2: Novel Trial Designs

Clinical Trial Design: Part 3: Biomarker-Directed Clinical Trials

Clinical Trial Design: Part 4

Controversies in Replication cfDNA Measurements

Deciphering and Targeting Lysosomes in Cancer

Defining the Significance of BRCA1 Variants of Unknown Significance

Defining Tumor Organ-systems with Single Cell Transcriptomics

Designing Biomarker Studies to Achieve Desired Clinical Applications

Game-Changing Technologies for High Through-Put Functional Characterization of Cancer Gene Variants

Metabolomic Methods for Cancer Research

Methods for Utilizing the Microbiome in Cancer Epidemiology Research

Modeling Tumor Dormancy

Novel Imaging Strategies in the Metastatic Niche

Peering through the Looking Glass: Imaging and the Metastatic Niche

Sample Size and Power Workshop for Basic, Translational, and Clinical Studies

Major Symposia Schedule24-Apr- 29-Apr-2020 @ 8:00 AM

AACR-Bayard D. Clarkson Symposium: Single-Cell Anaysis of Tumor Heterogeneity

Advancing Epigenetic Therapies for Solid Tumors

Artificial Intelligence and Machine Learning for Regulatory Use

At the Roots of Cancer: Biology and Regulation of the Hippo-YAP Pathway

Blood Biopsy for Response Monitoring

Bone Marrow Sensing of Distant Tumors: From Early Detection to Possible Therapy 

Cell-Based Therapies (Imm7)

The Changing Etiology of Liver Cancer: Needs for Prevention

Characterizing and Managing Cancer as a Complex Adaptive System 

Circadian Rhythms and Cancer

Clinical Trials and Clinical Utility 

Convergence of Artificial Intelligence, Big Data, and Prediction in Cancer 

Deregulation of Histone Modifiers in Cancer

Diverse Populations and Cancer

Earlier Detection of Cancer: Who to Screen, Where to Screen, and What to Screen?

Effects of Systemic Tumor-host Responses in Progression and Therapy Responses

Escaping Immune Surveillance

Evolution and Development of Resistance to Therapy 

FDA Special Session with Richard Pazdur

Genomic Instability

Germline-Somatic Interactions in Cancer Risk and Tumor Evolution 

Hematologic Malignancies

Immune Exhaustion in Cancer Therapies

Impact of a Brexit on Oncology Drug Development and Regulation

Interactions between the Local Microenvironment and the Cancer Cells in Progression and Therapy Responses

Liquid Biopsies: From Validation to Clinical Utility

Mammalian Sirtuins, Energy Bioenergetics, Metabolism, and Carcinogenesis

The Matrix Reloaded: Influences of the Extracellular Matrix on Tumor Progression

Metabolism: The New Kids on the Block in Cancer Care

Metastasis: Evidence and Clinical Implications of Early Dissemination 

The Microbiome as an Orchestrator of Immunity and Cancer Immunotherapy

Minimal Residual Disease: From Bench to Bedside 

Minorities in Cancer Research Scientific Symposium

Molecular Determinants and Dynamics of Metastasis

Multilevel Consideration of Cancer Health Disparities: Contextual Factors to Molecular Features 

The Next Generation of Precision Cancer Medicine:  Recognizing and Exploiting the Complexity

Obesity and Cancer: When Systemic Metabolism Cell Metabolism

Organ-Specific Immunity

Pediatric Oncology: Discovery, Development, Distribution

Prediagnostic Esposures and Tumor Mutational Signatures in Population Studies

Predictive Biomarkers

Presidential Select Symposium: Engaging Cancer Patients as Partners in the Research Process

Recently Approved Breakthrough Therapies and New Approval Endpoints

Regulation and Function of TP53 

Regulatory Considerations for Liquid Biopsy

The Science of Survivorship: Long-term Survivorship in Vulnerable Populations

Systematic Elucidation of Nononogene Targets

Systems Biology and Cancer Immunology

Systems Epigenetics in Hormone-Driven Cancers 

Tobacco Session

Transcriptional and Gene-Regulatory States: How They Relate to Lineage Origin and Plasticity in Pediatric Cancer

Tumor Metabolism and DNA Damage Response

Vascular Regulation of Anti-tumor Immunity

Diagnostics & Therapeutics Schedule24-Apr- 29-Apr-2020 @ 8:00 AM

Cooperativity of Tumor Clones

Innate Immunity and Complement in Solid Tumors

Intratumoral Approaches to Immunotherapy 

Liquid Biopsy in Brain Tumors and Metastases 

Modeling Treatment Response in Patient-Derived Organoids 

Molecular Imaging 

Nonpharmacologic Approaches to Improving Survival and Patient-Reported Outcomes 

Proton Therapy 

Recent Progress in Boron Neutron Capture Therapy

Regulation of the Immune Microenvironment by Glycosylation

The Remarkable Utility of Proximate Biologic Samples: Molecular Detection of Endometrial Cancer

RNA Editing in Cancer Pathophysiology

Small Molecule Protein Degraders

T-Cell Bispecifics: What Have We Learned About T-Cell Engagers in the Clinic?

Tumor Treating Fields- A Fourth Modality in Cancer Treatment

Vaccines

Organ Site Research Schedule24-Apr- 29-Apr-2020 @ 8:00 AM

Advances in Brain Metastases 

Advances in Gastric Cancer

Advances in Multiple Myeloma

Advances in Pancreatic Cancer 

Biologic Therapy Advances in Pediatric Tumors

The Changing Face of Ovarian Cancer 

Esophageal Cancer Equal Biology to Translational Medicine

Genetic Predisposition in Hematologic Malignancies

Genitourinary, Bladder, and Renal Cancers

Neuroendocrine Tumors: Genomics, Genetics, and Therapy

Small Cell Lung Cancer: A Glimmer of Light at the End of the Tunnel

Prevention, Interception & Cancer Health Disparities Schedule24-Apr- 29-Apr-2020 @ 8:00 AM

Advances in Prevention and Interception

Engineering Meets Biology

Role of Chronic Stress in the Etiology of Cancer 

Spectrum of Premalignant and Malignant Genomic Alterations in the “Healthy” Population 

Advances in the Science of Cancer Health Disparities

Novel Applications of Clinical Trials Research to Studying Disparities

The Science of Cancer Health Disparities

Forums Schedule24-Apr- 29-Apr-2020 @ 8:00 AM

B Cells in Solid Tumors: Good or Bad

Biden Cancer Initiative

Cancer Imaging: Separating the Hype from the Hope in Radiomics and Machine Learning

Challenges and Opportunities of International Consortia

The Changing Economics of Cancer

Drugging the Undruggable

Elimination of HPV and Related Cancers

Fighting the IL-1 Inflammatory Pathway

The Future of the In Vitro Clinical Test Regulation

Immuno-oncology Combination Trials: What Went Wrong?

Implementation Science for Evidence-Based Cancer Prevention and Early Detection Practices in Defined Diverse Populations

The Integration of Nanotechnologies and Bioengineering for Cancer Research

Minorities in Cancer Research Forum

The Science of Global Community Outreach

Science of Survivorship: The Intersection of Survivorship and Aging

Updates on Atlas Development
 

Meet-the-Experts Schedule24-Apr- 29-Apr-2020 @ 8:00 AM

A-I DNA Editing in Mutation and Diversity

The ALK Oncogene and Neuroblastoma - Yael P. Mosse, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

Amyloidosis - Suzanne Lentzsch, Columbia University, New York, New York

Approaches to Combination Therapy - Peter K. Sorger, Harvard Medical School, Boston, Massachusetts

ATAC Sequencing

Basic Immunology - Adrian Hayday, Francis Crick Institute, London, United Kingdom

Basic Immunology and Cancer Immunobiology

Big Data

Biology of Circulating Tumor Cells in Cancer Metastasis

Biomedical Informatics and Artificial Intellengence

Brain Tumor Biology: Malignant Networks in the Brain, and How to Target Them - Frank A. Winkler, German Cancer Research Center, Heidelberg, Germany

Breast Cancer Stem Cells: Translating Biology to the Clinic - Max S. Wicha, University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan

Chemical Methods to Decipher the Role of Individual Kinases and Their Cellular Signaling Networks

Circulating Cell-Free DNA to Guide Prostate Cancer Treatment with PARP Inhibition - Johann S. DeBono, Institute of Cancer Research, Sutton, United Kingdom

CODEX Multiplex Imaging

Combination Therapies: Immunotherapy and Radiation

Detection, Biology, and Clinical Relevance of CTC Clusters

Developmental Models of Pediatric Brain Tumors - Peter B. Dirks, The Hospital for Sick Children, Toronto, Ontario

Diet, the Gut Microbiome, and Colorectal Cancer - Andrew T. chan, Massachusetts General Hospital, Boston,Mas.

Disparities in Breast Cancer Prevention Research

DNA Repair

Drugging the Undruggable: The Myc Oncogene, as a Case Study

Engaging and Involving Patients in Translational Cancer Research - Bodour Salhia, University of Southern California

High Dimensional Analysis using Mass Cytometry - Kara L. Davis, Stanford University, Stanford, California

Immune Checkpoint Pathways, Melanoma, Surgery

Lung Cancer: Trials - Alice T. Shaw, Massachusetts General Hospital Cancer Center, Boston, Massachusetts

Metabolism: PI3K - Lewis C. Cantley, Weill Cornell Medical College, New York- Presbyterian Hospital, New York

Modeling of Pediatric Brain Tumors

Natural Killer Cells

New Single Cell Methods for Oncology and Immuno-oncology - James R. Heath, California Institute of Technology, Pasadena, California

Novel Radiopharmaceuticals for Cancer Diagnosis and  Diagnosis and Therapy, and Methods to Predict and Monitor the Response of  Tumors to Chemotherapy

Novel Therapeutic Strategies in Multiple Myeloma - Kenneth C. Anderson, Dana-Farber Cancer Institute, Boston

Obesity: Changing the Landscape for Cancer Risk in Populations

Prostate Cancer Health Disparity - Timothy R. Rebbeck, Harvard School of Public Health, Boston, Massachusetts

Radiation and Immunotherapy in Breast Cancer

Single Cell Genomics in Cancer to Deconvolute Tumor Heterogeneity

Systems Biology: Experimental and Mathematical, Computational Analysis

Universal Cancer Biomarker - Simple Test Using Gold Nanoparticles that Instantly Change Color to Determine if the 3D Nanostructures of Cancer DNA are Present - Matt Trau, The University of Queensland, Brisbane, Australia

Uses of CRISPR Technology in Translational Cancer Research - René Bernards, Netherlands Cancer Institute, Amsterdam

Using Zebrafish to Model Pediatric Cancer and Identify New Pathways for Targeted Drug Therapy - A. Thomas Look, Dana-Farber Cancer Institute, Boston, Massachusetts

What Cancer Genomes Tell Us About the Origins of Breast Cancer - Olufunmilayo I. Olopade, University of Chicago Medical Center, Chicago, Illinois

Plenary Sessions Schedule24-Apr- 27-Apr-2020 @ 8:00 AM

Friday, April 24, 2020
Opening Plenary
Achieving Equitable Patient Care through Precision and Convergent Cancer Science
Chair: John D. Carpten, University of Southern California Keck School of Medicine, Los Angeles, California

Physicist vs. physician: Digitizing clinical assessment, and using it for evidence-based prediction of outcomes
Peter Kuhn, University of Southern California Michelson Center for Convergent Bioscience, Los Angeles, California

Title to be announced
Jorge J. Nieva, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California

Therapeutic implications of DNA repair defects in cancer
Alan Ashworth, University of California San Francisco Helen Diller Family Comprehensive Cancer Center, San Francisco, California

Defining the actionable genome
David B. Solit, Memorial Sloan Kettering Cancer Center, New York, New York

Title to be announced
Levi A. Garraway, Eli Lilly and Company, Indianapolis, Indiana 

Next generation CAR T cells designed to overcome tumor resistance
Crystal L. Mackall, Stanford University School of Medicine, Stanford, California

Title to be announced
E. John Wherry, University of Pennsylvania, Philadelphia, Pennsylvania


Saturday, April 25, 2020
Clinical and Translational Research in Diverse Populations
Chair: Lisa A. Newman, Weill Cornell Medicine, New York, New York

Title to be announced
Olusegun I. Alatise, Obafemi Awolowo University, Ile-Ife, Osun, Nigeria

Spliceomics: Alternative RNA splicing as a source of ancestry-related molecular targets in precision oncology and cancer disparities
Steven R. Patierno, Duke Cancer Institute, Durham, North Carolina

The DARC side of breast cancer disparities: Links to African ancestry and immunological tumor responses
Melissa B. Davis, Weill Cornell Medicine, New York, New York

Genomic and epigenomic studies of Cholangiocarcinoma in diverse populations
Bin Tean Teh, National Cancer Center Singapore, Singapore

 

Sunday, April 26, 2020
Manipulating the Immune System in Cancer Therapy 
Chair: Padmanee Sharma, The University of Texas MD Anderson Cancer Center, Houston, Texas
 

T-cell therapy targeting unique cancer mutations
Steven A. Rosenberg, National Cancer Institute, Bethesda, Maryland

Redirecting T-cells for cancer immunotherapy using next generation bispecific antibodies and fusion proteins
Pablo Umana, Roche Innovation Center Zurich, Zurich, Switzerland 

Taming the beast: Strategies to target the immune suppressive macrophage to enhance cancer immune therapy
Judith A. Varner, University of California San Diego Moores Cancer Center, La Jolla, California

Mismatch repair deficiency: A connection between the immune system and cancer genetics
Dung T. Le, Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland
 

Monday, April 27, 2020
Pathogen-Related Cancers: Implications for Populations and Public Health 
Chair: Douglas R. Lowy, National Cancer Institute, Bethesda, Maryland

Screening nasopharyngeal carcinoma using plasma Epstein-Barr virus DNA: technological and clinical insights
Yuk Ming Dennis Lo, The Chinese University of Hong Kong, Shatin, Hong Kong

Hepatitis B and C virus-related hepatocellular carcinoma in the era of highly active antiviral therapies
Jean-Michel Pawlotsky, Institut Mondor de Recherche Biomédicale, INSERM U955, Créteil, France

HIV and cancer: From despair to gene therapy
Ariela Noy, Memorial Sloan Kettering Cancer Center, New York, New York

Title to be announced
Cornelia L. Trimble, Johns Hopkins University, Baltimore, Maryland

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